Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935448 | 0.87 | CNR2 (0.42) | CFTRMMP2MMP9MMP8L3MBTL1 | |
| SCHEMBL6935775 | 0.85 | CFTR (0.48) | CFTRL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6933141 | 0.84 | PGR (0.43) | CFTRMMP2MMP9MMP8ALDH1A1 | |
| SCHEMBL6936622 | 0.81 | ALDH1A1 (0.44) | MMP2MMP9MMP8ALDH1A1MAPT | |
| SCHEMBL6935772 | 0.81 | PGR (0.44) | MMP2MMP9MMP8ALDH1A1MAPT | |
| SCHEMBL6935614 | 0.79 | ALDH1A1 (0.46) | MMP2MMP9MMP8L3MBTL1ALDH1A1 | |
| SCHEMBL6931194 | 0.78 | MAPT (0.45) | L3MBTL1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6931193 | 0.78 | HDAC4 (0.43) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6933114 | 0.75 | CNR1 (0.46) | ALDH1A1MAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL6932783 | 0.75 | MAPT (0.48) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |