SCHEMBL6933602

SCHEMBL6933602

C=C(C)c1cccc2sc3ccccc3c(=O)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
ALDH1A1 P00352 6/20 0.48
POLB P06746 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
HPGD P15428 2/20 0.48
GAA P10253 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
GPR3 P46089 1/20 0.39
HCRTR1 O43613 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17524731 0.87 GPR3 (0.45) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL10793109 0.86 MAPT (0.49) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL30835138 0.86 MAPT (0.49) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL21624239 0.82 MAOA (0.51) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL2021523 0.81 MAOA (0.50) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL3257120 0.79 MAOA (0.49) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL9291222 0.79 MAOB (0.49) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL29494120 0.79 MAPT (0.52) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL52314 0.79 MAPT (0.52) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL27746362 0.79 MAPT (0.46) MAPTALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2961520-B1 POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2016-07-20 EP disclosed
US-20160001237-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2016-01-07 US disclosed
EP-2961521-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER Wacker Chemie AG (DE) 2016-01-06 EP disclosed
EP-2961520-A1 POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER Wacker Chemie AG (DE) 2016-01-06 EP disclosed
US-20150376365-A1 POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2015-12-31 US disclosed
WO-2014131706-A1 POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2014-09-04 WO disclosed
WO-2014131673-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2014-09-04 WO disclosed
WO-2014114501-A1 NON-WOVENS MADE OF THERMOPLASTIC SILICONE ELASTOMERS, PRODUCIBLE BY MEANS OF ELECTRO SPINNING WACKER CHEMIE AG (DE) 2014-07-31 WO disclosed
WO-2014063960-A1 POROUS MEMBRANES MADE OF CROSSLINKED SILICONE COMPOSITIONS WACKER CHEMIE AG (DE) 2014-05-01 WO disclosed
EP-0892023-B1 Opaque pigment flakes CIBA SC HOLDING AG (CH) 2003-12-03 EP disclosed
WO-1999037701-A1 SIDE-CHAIN LIQUID CRYSTALLINE POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-07-29 WO disclosed
EP-0892023-A1 Opaque pigment flakes Ciba SC Holding AG (CH) 1999-01-20 EP disclosed
US-5641850-A HYDROSILATION OF A HYDRIDOPOLYSILOXANE BY AN ALKENE CONTAINING MESOGENIC GROUPS FOLLOWED BY REACTION WITH AN ALKENE CONTAINING A (METH)ACRYLOXY GROUP; CROSSLINKING; HAZE-FREE FILMS CONSORTIUM FUR ELECTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-06-24 US disclosed
EP-0711780-A1 Process for the preparation of liquid crystalline polyorganosiloxanes containing (meth-)acryloxy groups Consortium für elektrochemische Industrie GmbH (DE) 1996-05-15 EP disclosed
EP-0358208-B1 Liquid crystal polyorganosiloxanes containing (meth)acryloxy groups CONSORTIUM ELEKTROCHEM IND (DE) 1994-03-02 EP disclosed
EP-0508491-B1 (Meth)acryloxy-functional organosilicon compounds, their preparation and their use WACKER CHEMIE GMBH (DE) 1994-01-26 EP disclosed
US-5214077-A ORGANOSILICON COMPOUNDS CONTAINING (METH)ACRYLOXY GROUPS, THEIR PREPARATION AND USE WACKER-CHEMIE GMBH (DE) 1993-05-25 US disclosed
US-5211877-A Crosslinked resins CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-05-18 US disclosed
EP-0508491-A1 (Meth)acryloxy-functional organosilicon compounds, their preparation and their use WACKER-CHEMIE GMBH (DE) 1992-10-14 EP disclosed
EP-0358208-A2 Liquid crystal polyorganosiloxanes containing (meth)acryloxy groups Consortium für elektrochemische Industrie GmbH (DE) 1990-03-14 EP disclosed