Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933850 | 0.81 | HPGD (0.44) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6930598 | 0.77 | HPGD (0.41) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6934098 | 0.77 | HPGD (0.41) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6933627 | 0.76 | PDE4A (0.41) | GAAALDH1A1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6934231 | 0.75 | ALDH1A1 (0.44) | HPGDGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL6935099 | 0.72 | PDE4A (0.36) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6933851 | 0.69 | PDE4A (0.41) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6928265 | 0.66 | GAA (0.39) | GAATDP1 | |
| SCHEMBL3734888 | 0.60 | HPGD (0.51) | HPGDGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL7468319 | 0.59 | ALDH1A1 (0.50) | HPGDGAAKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |