Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933850 | 0.79 | HPGD (0.44) | ALDH1A1SMN1; SMN2GAALMNAHPGD | |
| SCHEMBL6936525 | 0.78 | GAA (0.39) | ALDH1A1SMN1; SMN2GAAPOLBMAPT | |
| SCHEMBL8489121 | 0.77 | APP (0.43) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL6934098 | 0.75 | HPGD (0.41) | ALDH1A1SMN1; SMN2NPSR1HSD17B10GAA | |
| SCHEMBL6930598 | 0.75 | HPGD (0.41) | ALDH1A1SMN1; SMN2NPSR1HSD17B10GAA | |
| SCHEMBL6933636 | 0.75 | HPGD (0.41) | ALDH1A1SMN1; SMN2NPSR1HSD17B10GAA | |
| SCHEMBL6930285 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL6733485 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPSR1HSD17B10GAA | |
| SCHEMBL6936608 | 0.73 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPSR1HSD17B10GAA | |
| SCHEMBL6928227 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2NPSR1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |