SCHEMBL6933903

SCHEMBL6933903

CCCCCCC(=O)C1CC1c1cccc(OCc2ccccc2/C(=C\OC)C(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.35
CNR2 P34972 6/20 0.35
FFAR1 O14842 1/20 0.34
SLC9A1 P19634 1/20 0.34
CNR1 P21554 3/20 0.34
PPARA Q07869 2/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933907 1.00 HIF1A (0.35) HIF1ACNR2FFAR1SLC9A1CNR1
SCHEMBL6933910 0.86 HIF1A (0.37) HIF1ACNR2FFAR1SLC9A1CNR1
SCHEMBL8077603 0.84 HIF1A (0.39) HIF1AFFAR1SLC9A1
SCHEMBL8077602 0.84 HIF1A (0.39) HIF1AFFAR1SLC9A1
SCHEMBL8083996 0.84 HIF1A (0.41) HIF1A
SCHEMBL8083999 0.84 HIF1A (0.41) HIF1A
SCHEMBL8077647 0.82 HIF1A (0.36) HIF1AFFAR1SLC9A1
SCHEMBL6934748 0.77 HIF1A (0.39) HIF1A
SCHEMBL8082320 0.77 HIF1A (0.36) HIF1A
SCHEMBL8082315 0.77 HIF1A (0.36) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1050528-B1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds DOW AGROSCIENCES LLC (US) 2003-01-22 EP disclosed
US-6335367-B1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds DOW AGROSCIENCES LLC 2002-01-01 US disclosed
EP-1050528-A1 Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds ROHM AND HAAS COMPANY (US) 2000-11-08 EP disclosed