Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933903 | 0.86 | HIF1A (0.35) | HIF1ACNR2FFAR1SLC9A1CNR1 | |
| SCHEMBL6933907 | 0.86 | HIF1A (0.35) | HIF1ACNR2FFAR1SLC9A1CNR1 | |
| SCHEMBL8077605 | 0.84 | HIF1A (0.41) | HIF1ASLC9A1L3MBTL1DGAT2 | |
| SCHEMBL6940894 | 0.72 | OPRM1 (0.48) | CNR2CNR1HTR2A | |
| SCHEMBL8077603 | 0.69 | HIF1A (0.39) | HIF1AFFAR1SLC9A1L3MBTL1 | |
| SCHEMBL8077602 | 0.69 | HIF1A (0.39) | HIF1AFFAR1SLC9A1L3MBTL1 | |
| SCHEMBL8079208 | 0.68 | HIF1A (0.47) | HIF1ADGAT2 | |
| SCHEMBL8079209 | 0.68 | HIF1A (0.47) | HIF1ADGAT2 | |
| SCHEMBL17029589 | 0.68 | HRH3 (0.51) | SLC9A1 | |
| SCHEMBL8083996 | 0.68 | HIF1A (0.41) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050528-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6335367-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC | 2002-01-01 | — | — | US | disclosed |
| EP-1050528-A1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | ROHM AND HAAS COMPANY (US) | 2000-11-08 | — | — | EP | disclosed |