SCHEMBL6934057

SCHEMBL6934057

Cc1ccc(COO)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
PYCR1 P32322 1/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
CASP1 P29466 1/20 0.39
HBB P68871 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KDM4A O75164 1/20 0.39
KDM5A P29375 1/20 0.39
KDM2B Q8NHM5 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8516081 0.82 ALDH1A1 (0.44) TP53TDP1KDM4EALDH1A1PYCR1
SCHEMBL30618212 0.82 ALDH1A1 (0.44) TP53TDP1KDM4EALDH1A1PYCR1
SCHEMBL15012476 0.82 ALDH1A1 (0.44) TP53TDP1KDM4EALDH1A1PYCR1
SCHEMBL10777398 0.81 ESR1 (0.38) NPC1RAB9A
SCHEMBL1145658 0.80 KDM4E (0.51) TP53TDP1KDM4EALDH1A1PYCR1
SCHEMBL1145655 0.78 KDM4E (0.42) TP53TDP1KDM4EALDH1A1PYCR1
SCHEMBL6667424 0.78 SMN1; SMN2 (0.50) TP53TDP1KDM4EALDH1A1KMT2A
SCHEMBL3432857 0.77 KDM4E (0.41) TP53TDP1KDM4EALDH1A1PYCR1
Hydrochloric Acid SCHEMBL31019680 0.77 AGXT (0.52) KDM4EALDH1A1PYCR1TAAR1
SCHEMBL11467418 0.76 SMN1; SMN2 (0.49) TP53TDP1KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1366006-A1 PROCESS FOR PREPARING PHENOLS INEOS Phenol GmbH & Co. KG (DE) 2003-12-03 EP disclosed
WO-2002070442-A1 PROCESS FOR PREPARING PHENOLS INEOS PHENOL GMBH & CO. KG (DE) 2002-09-12 WO disclosed
US-3978141-A PROCESS FOR SPLITTING ALKYLAROMATIC HYDROPEROXIDES INTO PHENOLIC COMPOUNDS RHONE-POULENC S.A. (FR) 1976-08-31 US disclosed
US-3948995-A Process for converting alkylaromatic hydroperoxides into phenolic products and carbonyl products RHONE-POULENC-TEXTILE (FR) 1976-04-06 US disclosed