Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991938 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL31313 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL5068661 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| P-Xylene SCHEMBL8660591 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL34 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL11432043 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL1705904 | 0.66 | GAA (0.62) | KDM4EALDH1A1LMNAMAPTHTT | |
| Water SCHEMBL28198696 | 0.65 | GAA (0.54) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL3180429 | 0.65 | GAA (0.59) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL1594407 | 0.65 | GAA (0.59) | KDM4EALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506539-B2 | Recording; compact disks, television; complex of cyanine dye and tetracyanoquinodmethane compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| US-20020025491-A1 | Dye complex and optical information recording medium | FUJIFILM CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| EP-1142961-A2 | Dye complex and optical information recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |