Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241805 | 1.00 | NAAA (0.56) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL6239340 | 1.00 | NAAA (0.56) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL6930474 | 1.00 | NAAA (0.56) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL6241121 | 0.85 | TLR2 (0.51) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL506861 | 0.85 | TLR2 (0.53) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL506862 | 0.85 | TLR2 (0.53) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL6239432 | 0.84 | POLB (0.49) | CA12CA2CA9POLBMAPK1 | |
| SCHEMBL15232424 | 0.83 | POLB (0.47) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL16506631 | 0.83 | POLB (0.47) | NAAACA12CA2CA9TLR2 | |
| SCHEMBL6936553 | 0.82 | TLR2 (0.58) | NAAATLR2ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869115-B1 | Amino acid derivatives and compositions containing the same for inhibiting active-oxygen | AJINOMOTO KK (JP) | 2003-12-17 | — | — | EP | disclosed |
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-5985922-A | Amino acid derivatives and active oxygen-resisting agent | AJINOMOTO CO., INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |
| EP-0869115-A2 | Amino acid derivatives and compositions containing the same for inhibiting active-oxygen | Ajinomoto Co., Inc. (JP) | 1998-10-07 | — | — | EP | disclosed |