SCHEMBL6934366

SCHEMBL6934366

O=[N+]([O-])c1cc(-c2ccccc2)c([N+](=O)[O-])c([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
TDP1 Q9NUW8 2/20 0.58
HPRT1 P00492 1/20 0.54
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
MEN1 O00255 1/20 0.48
PSMD14 O00487 1/20 0.48
PRKACA P17612 1/20 0.48
CASP6 P55212 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
STAT6 P42226 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29914892 0.96 HPRT1 (0.59) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL2825162 0.86 ALDH1A1 (0.47) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL27548148 0.86 ALDH1A1 (0.55) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL5707211 0.84 CRHBP (0.57) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL2832444 0.84 ALDH1A1 (0.45) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL7051300 0.83 ALDH1A1 (0.60) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL15941658 0.83 TDP1 (0.40) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL15461976 0.82 ALDH1A1 (0.69) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL11840696 0.81 HPRT1 (0.54) ALDH1A1TDP1HPRT1CRHBPCRHR2
SCHEMBL28274440 0.81 TDP1 (0.53) ALDH1A1TDP1HPRT1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030053936-A1 Opto-acoustic wave chemical sensor GENERAL ELECTRIC COMPANY 2003-03-20 US claimed
US-20030040118-A1 Apparatus and method for spatially detecting or quantifying chemical species GENERAL ELECTRIC COMPANY 2003-02-27 US claimed
CN-116621840-A 6-nitro-7-amino- [1,2,4] triazole [1,5-a ] pyrimidine, synthesis method and application 西安近代化学研究所 2023-08-22 CN disclosed
CN-108409576-B Method for nitrating aromatic compound with nitrate under action of adjuvant 中国人民大学 2021-03-02 CN disclosed
US-20190072493-A1 DEVICE AND METHOD FOR ON-CHIP CHEMICAL SEPARATION AND DETECTION OREGON STATE UNIVERSITY (US) 2019-03-07 US disclosed
CN-103922941-A Method for synthesizing 2,4-dinitrobenzoic acid UNIV NORTH CHINA 2014-07-16 CN disclosed
US-6787366-B1 COMPRISES PLACING A CHROMOGENIC OR FLUOROGENIC DETECTOR REAGENT ON A CHROMATOGRAPHIC SHEET CONTAINING SORBENT MATERIAL; CAPILLARY TUBES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2004-09-07 US disclosed
US-6420181-B1 DETECTING PREFERENTIAL PARTICLE IN SOLUTION; OBTAIN SOLUTION CONTAINING PARTICLE, MIX WITH SOLVENT, INSERT INTO TUBE, INCUBATE WITH CHROMOGENIC DETECTION INDICATOR, MONITOR SAMPLE FOR SIGNAL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2002-07-16 US disclosed