Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775489 | 0.81 | FFAR1 (0.50) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL28669621 | 0.81 | FFAR1 (0.50) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL25169879 | 0.81 | FFAR1 (0.50) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL28678691 | 0.81 | FFAR1 (0.50) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL8079247 | 0.81 | CHRNB4 (0.48) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL8013432 | 0.76 | MGLL (0.46) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL6940161 | 0.74 | CHRNB4 (0.45) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL23940041 | 0.73 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL23923444 | 0.73 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL23923443 | 0.73 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050528-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6335367-B1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | DOW AGROSCIENCES LLC | 2002-01-01 | — | — | US | disclosed |
| EP-1050528-A1 | Fungicidal and insecticidal benzyloxy cyclopropyl substituted aromatic compounds | ROHM AND HAAS COMPANY (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-0889024-B1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM & HAAS (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5945557-A | PHENYL DERIVATIVES WHICH POSSESS A SUBSTITUTED CYCLOPROPYL MOIETY; USEFUL AGAINST POWDERY MILDEW, BLIGHT AND OTHER PLATN DISEASES; INSECTICIDES AGAINST SOUTHERN ARMYWORM, MEXICAN BEAN BEETLE AND SPIDER MITES, FOR EXAMPLE | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0889024-A1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |