SCHEMBL6934790

SCHEMBL6934790

C=C(C)C(=O)OCCOC(=O)C=CC=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 5/20 0.52
AKR1B1 P15121 5/20 0.52
MAOB P27338 3/20 0.46
APP P05067 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 2/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934789 1.00 AKR1B10 (0.52) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL3085092 0.90 AKR1B10 (0.64) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL554600 0.90 AKR1B10 (0.64) AKR1B10AKR1B1MAOBAPPALDH1A1
Styrene SCHEMBL28724567 0.85 AKR1B10 (0.58) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL13836018 0.85 AKR1B10 (0.57) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL10061424 0.85 AKR1B10 (0.57) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL11880040 0.83 AKR1B10 (0.56) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL9880793 0.83 AKR1B10 (0.55) AKR1B10AKR1B1MAOBAPPALDH1A1
SCHEMBL14877957 0.81 AKR1B10 (0.55) AKR1B10AKR1B1MAOBAPPALDH1A1
Juarezic Acid SCHEMBL28729155 0.81 RAB9A (0.50) MAOBALDH1A1LMNAHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747704-B1 Immunoassay element containing a diaryl telluride compound to increase its stability ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-12-10 EP disclosed
EP-0903583-B1 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-11-12 EP disclosed
EP-0684473-B1 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions JOHNSON & JOHNSON CLIN DIAG (US) 2001-11-07 EP disclosed
EP-0699908-B1 Immunoassay elements having stable leuco dye coatings JOHNSON & JOHNSON CLIN DIAG (US) 2000-11-22 EP disclosed
EP-0675362-B1 Minimizing interferences in chemiluminescent thin-film immunoassays JOHNSON & JOHNSON CLIN DIAG (US) 2000-09-27 EP disclosed
US-6090568-A Format for minimizing interferences in chemiluminescent thin-film immunoassays CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) 2000-07-18 US disclosed
EP-0699905-B1 Leuco dye coating compositions JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-17 EP disclosed
US-5928886-A SUPPORT HAVING ZONE OF ENZYME LABELED LIGAND OR ENZYME LABELED RECEPTOR, SPREADING ZONE, ZONE OF IMMOBILIZED RECEPTOR OF LIGAND, AND GRAVURE ZONE WITH DIARYL TELLURIDE; INCREASED STORAGE STABILITY JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-07-27 US disclosed
US-5888719-A CONTINING A POLYMER; DARK DECAY STABILITY AGFA-GEVAERT AG (DE) 1999-03-30 US disclosed
EP-0903583-A2 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements Ortho-Clinical Diagnostics, Inc. (US) 1999-03-24 EP disclosed
EP-0146337-B1 ELEMENTS HAVING HYDROPHILIC LAYERS CONTAINING HYDROPHOBES IN POLYMER PARTICLES AND A METHOD OF MAKING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-05-02 EP disclosed
US-4865946-A CROSSLINKED KETO-SUBSTITUTED ACRYLAMIDE COPOLYMER EASTMAN KODAK COMPANY (US) 1989-09-12 US disclosed
EP-0266410-A1 IMAGING ELEMENTS HAVING HYDROPHILIC LAYERS CONTAINING HYDROPHOBES IN POLYMER PARTICLES AND METHOD FOR MANUFACTURE THEREOF. EASTMAN KODAK CO (US) 1988-05-11 EP disclosed
WO-1987006723-A2 IMAGING ELEMENTS HAVING HYDROPHILIC LAYERS CONTAINING HYDROPHOBES IN POLYMER PARTICLES AND METHOD FOR MANUFACTURE THEREOF EASTMAN KODAK COMPANY (US) 1987-11-05 WO disclosed
US-4684605-A COLOR PHOTOGRAPHIC PAPER EASTMAN KODAK COMPANY (US) 1987-08-04 US disclosed
US-4584255-A CRYSTAL- AND AGGLOMERATION-FREE HYDROPHILIC LAYER EASTMAN KODAK COMPANY (US) 1986-04-22 US disclosed
EP-0146337-A2 Elements having hydrophilic layers containing hydrophobes in polymer particles and a method of making same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-06-26 EP disclosed
EP-0137672-A2 Photographic material with a barrier layer comprising a chill-gelable polymer and a method for coating it EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-17 EP disclosed
US-4504569-A OF AN ACRYLAMIDE EASTMAN KODAK COMPANY (US) 1985-03-12 US disclosed
EP-0121141-A2 Chill-gelable polymers and their use EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-10 EP disclosed