Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28378440 | 0.91 | HSD17B10 (0.44) | ITGB1ITGA5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8062430 | 0.89 | HSD17B10 (0.43) | ITGB1ITGA5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10791915 | 0.86 | KDM4E (0.41) | ITGB1ITGA5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2838029 | 0.85 | HSD17B10 (0.50) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL5709712 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10GAATSHR | |
| SCHEMBL6936536 | 0.80 | LCK (0.40) | ITGB1ITGA5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3775895 | 0.80 | ALDH1A1 (0.47) | ITGB1ITGA5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL123279 | 0.80 | TSHR (0.47) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL6941398 | 0.79 | PTPN11 (0.46) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8466485 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |