Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929773 | 0.92 | CES2 (0.57) | KDM4ECES2CES1HPGDSMN1; SMN2 | |
| SCHEMBL11898841 | 0.85 | KDM4E (0.39) | PTPN11KDM4ELCKHPGDSMN1; SMN2 | |
| SCHEMBL123279 | 0.84 | TSHR (0.47) | KDM4EHPGDSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL11899850 | 0.83 | KDM4E (0.38) | PTPN11KDM4ELCKHPGDSMN1; SMN2 | |
| SCHEMBL14612271 | 0.82 | SMN1; SMN2 (0.36) | PTPN11KDM4ELCKHPGDSMN1; SMN2 | |
| SCHEMBL123941 | 0.80 | TDP1 (0.44) | CES2CES1RAB9AALDH1A1MAPT | |
| SCHEMBL6936536 | 0.80 | LCK (0.40) | PTPN11KDM4ELCKCYP2A6HPGD | |
| SCHEMBL6934811 | 0.79 | ITGB1 (0.43) | KDM4EHPGDSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL6934827 | 0.79 | ALDH1A1 (0.47) | KDM4ERAB9AALDH1A1MAPTCA12 | |
| SCHEMBL8422950 | 0.78 | KDM4E (0.60) | KDM4ECES2CES1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |