Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935216 | 1.00 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6933161 | 0.88 | CYP1A2 (0.56) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6933166 | 0.88 | CYP1A2 (0.56) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6932992 | 0.87 | CYP1A2 (0.73) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6932989 | 0.87 | CYP1A2 (0.73) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6935938 | 0.86 | OPRD1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6935942 | 0.86 | OPRD1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6937064 | 0.83 | CYP1A2 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6937062 | 0.83 | CYP1A2 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6935573 | 0.82 | OPRD1 (0.80) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649414-B1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | ARDENT PHARMACEUTICALS INC (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0649414-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993015062-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |