Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27679756 | 0.83 | ALDH1A1 (0.37) | PKMMEN1KMT2ALMNANPSR1 | |
| SCHEMBL692648 | 0.75 | DYRK1A (0.44) | PKMMEN1KMT2ALMNANPSR1 | |
| SCHEMBL123488 | 0.74 | CYP19A1 (0.51) | KMT2ALMNACA2CA12CA9 | |
| SCHEMBL16376504 | 0.72 | CYP19A1 (0.53) | LMNACA2CA12CA9CA1 | |
| SCHEMBL2799834 | 0.71 | SMN1; SMN2 (0.56) | PKMMEN1KMT2ALMNACA12 | |
| SCHEMBL8381918 | 0.71 | MAOB (0.51) | PKMMEN1KMT2ALMNACA2 | |
| SCHEMBL11886576 | 0.70 | MAOB (0.49) | CA2CA12CA9CA1 | |
| SCHEMBL123183 | 0.70 | CA12 (0.42) | PKMLMNAF2F10CA2 | |
| SCHEMBL3617999 | 0.70 | APP (0.38) | F2F10LOXL2CYP19A1 | |
| SCHEMBL8133718 | 0.70 | CYP2A6 (0.47) | F2F10LOXL2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997363-B | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS | 2012-03-28 | — | — | CN | disclosed |
| EP-2422780-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2422781-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| CN-1997363-A | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS (US) | 2007-07-11 | — | — | CN | disclosed |