Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27679752 | 0.81 | SNCA (0.44) | DYRK1APKMKMT2AMEN1NPSR1 | |
| SCHEMBL22587550 | 0.77 | MAOB (0.50) | KMT2AMEN1NPSR1CA12CA2 | |
| SCHEMBL2799834 | 0.75 | SMN1; SMN2 (0.56) | PKMKMT2AMEN1LMNACA12 | |
| SCHEMBL693536 | 0.75 | PKM (0.33) | PKMKMT2AMEN1NPSR1F10 | |
| SCHEMBL25262259 | 0.73 | TP53 (0.44) | KMT2AMEN1LMNACA12CA2 | |
| SCHEMBL25988418 | 0.72 | GAA (0.49) | PKMKMT2AMEN1NPSR1LMNA | |
| SCHEMBL17364507 | 0.72 | BRPF1 (0.44) | DYRK1APKMKMT2AMEN1LMNA | |
| SCHEMBL6809812 | 0.71 | CA1 (0.44) | CA1CA2CA9 | |
| SCHEMBL30357699 | 0.71 | LMNA (0.48) | LMNACA1CA2CA9ALDH1A1 | |
| SCHEMBL2263563 | 0.71 | LMNA (0.48) | LMNACA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997363-B | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS | 2012-03-28 | — | — | CN | disclosed |
| EP-2422780-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2422781-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| CN-1997363-A | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS (US) | 2007-07-11 | — | — | CN | disclosed |