Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936097 | 0.87 | KDM4E (0.45) | KDM4EHTTSMPD1TLR8MAPT | |
| SCHEMBL6934383 | 0.85 | SMPD1 (0.43) | ALDH1A1SMPD1TLR8CNR1MAPT | |
| SCHEMBL6934809 | 0.84 | ELANE (0.37) | KDM4EALDH1A1POLBMAPTLMNA | |
| SCHEMBL6932869 | 0.76 | TLR8 (0.46) | TLR8CNR1 | |
| SCHEMBL6934861 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1CNR1 | |
| SCHEMBL6935448 | 0.75 | CNR2 (0.42) | HTTALDH1A1CNR1MAPTLMNA | |
| SCHEMBL6933518 | 0.73 | ALDH1A1 (0.46) | KDM4EHTTALDH1A1POLBGAA | |
| SCHEMBL7615014 | 0.72 | KDM4E (0.47) | KDM4EHTTALDH1A1POLBSMPD1 | |
| SCHEMBL6934453 | 0.68 | MAPT (0.43) | KDM4EHTTALDH1A1GAACNR1 | |
| SCHEMBL6933855 | 0.65 | ALDH1A1 (0.46) | KDM4EALDH1A1POLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |