Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935385 | 0.87 | KDM4E (0.47) | KDM4ELMNAHTTNPSR1MAPT | |
| SCHEMBL6934383 | 0.85 | SMPD1 (0.43) | MAPTSMPD1TLR8 | |
| SCHEMBL6932869 | 0.83 | TLR8 (0.46) | TLR8 | |
| SCHEMBL6935448 | 0.81 | CNR2 (0.42) | LMNAHTTNPSR1MAPT | |
| SCHEMBL6933855 | 0.76 | ALDH1A1 (0.46) | KDM4ELMNA | |
| SCHEMBL6933518 | 0.75 | ALDH1A1 (0.46) | KDM4ELMNAHTTNPSR1MAPT | |
| SCHEMBL7606893 | 0.70 | KDM4E (0.45) | KDM4ELMNAHTTNPSR1MAPT | |
| SCHEMBL6931339 | 0.70 | ALDH1A1 (0.43) | LMNAHTTNPSR1 | |
| SCHEMBL6931535 | 0.68 | OPRL1 (0.37) | KDM4EPKM | |
| SCHEMBL6931581 | 0.67 | ALDH1A1 (0.42) | KDM4ELMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |