Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 5/20 | 0.67 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 9/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935463 | 1.00 | KCNE1 (0.67) | KCNE1KCNQ1KCNA5ABCB1HIF1A | |
| SCHEMBL6932410 | 0.80 | KCNE1 (1.00) | KCNE1KCNQ1HIF1A | |
| SCHEMBL6932409 | 0.80 | KCNE1 (1.00) | KCNE1KCNQ1HIF1A | |
| SCHEMBL6931989 | 0.80 | KCNE1 (0.68) | KCNE1KCNQ1KCNA5ABCB1MAOB | |
| SCHEMBL6603299 | 0.79 | KCNE1 (0.54) | KCNE1KCNQ1MAOB | |
| SCHEMBL8479087 | 0.77 | KCNE1 (0.76) | KCNE1KCNQ1KCNA5ABCB1HIF1A | |
| SCHEMBL6934369 | 0.77 | KCNE1 (0.61) | KCNE1KCNQ1HIF1AMAOB | |
| SCHEMBL6930496 | 0.76 | KCNE1 (0.73) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL6930493 | 0.76 | KCNE1 (0.73) | KCNE1KCNQ1KCNA5 | |
| SCHEMBL7477965 | 0.75 | KCNE1 (0.60) | KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913396-B1 | Sulphonamide substituted benzopyran derivatives, process of preparation, their use as medicines and pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-0913396-A2 | Sulphonamide substituted benzopyran derivatives, process of preparation, their use as medicines and pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-05-06 | — | — | EP | disclosed |