Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938541 | 0.90 | SLC9A1 (0.64) | SLC9A1 | |
| SCHEMBL6936965 | 0.87 | — | — | |
| SCHEMBL7798517 | 0.87 | SLC9A1 (0.60) | SLC9A1 | |
| SCHEMBL6933370 | 0.87 | SLC9A1 (0.60) | SLC9A1 | |
| SCHEMBL7798363 | 0.85 | SLC9A1 (0.64) | SLC9A1 | |
| SCHEMBL9192614 | 0.84 | SLC9A1 (0.53) | SLC9A1 | |
| SCHEMBL6935220 | 0.84 | SLC9A1 (0.56) | SLC9A1 | |
| SCHEMBL8925101 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL6937449 | 0.83 | SLC9A1 (0.61) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8816000 | 0.83 | SLC9A1 (0.52) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0725062-B1 | 4-mercapto-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5696167-A | 4-mercaptobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0725062-A1 | 4-mercapto-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-08-07 | — | — | EP | disclosed |