SCHEMBL6935628

SCHEMBL6935628

Cc1nn(C)c(NCCN2CCNCC2)c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 2/20 0.44
TLR8 Q9NR97 1/20 0.41
TLR7 Q9NYK1 1/20 0.41
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
HSD17B10 Q99714 2/20 0.36
KHK P50053 1/20 0.35
P2RX3 P56373 1/20 0.35
P2RX2 Q9UBL9 1/20 0.35
RAD52 P43351 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ANPEP P15144 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934682 0.85 NMT1 (0.42) NMT1TLR8TLR7L3MBTL1ALDH1A1
SCHEMBL6934565 0.79 KDM4E (0.35) SMN1; SMN2KDM4EGAA
SCHEMBL1801275 0.73 KDM4E (0.35) CYP2D6HSD17B10ALDH1A1MEN1KMT2A
SCHEMBL6935626 0.72 CXCR4 (0.30)
SCHEMBL6934679 0.72 CYP1A2 (0.37) CYP3A4CYP2D6SMN1; SMN2KCNH2
SCHEMBL6967173 0.70 KDM4E (0.33) SMN1; SMN2KDM4EGAA
SCHEMBL7114634 0.68 MAPT (0.39) SMN1; SMN2KDM4EGAA
SCHEMBL6934711 0.67 SMN1; SMN2 (0.37) HSD17B10L3MBTL1ALDH1A1TSHRMEN1
SCHEMBL6937423 0.67 NPC1 (0.44) CYP3A4CYP2D6L3MBTL1ALDH1A1TSHR
SCHEMBL1805254 0.66 GAA (0.36) POLBSMN1; SMN2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304995-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-05-02 EP claimed
WO-2002009662-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO claimed
EP-1304995-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-05-02 EP disclosed
WO-2002009662-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO disclosed