Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459103 | 0.85 | ADRB3 (0.43) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL6934131 | 0.85 | ADRB3 (0.44) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL6938695 | 0.83 | MAPT (0.53) | ADRB3MEN1KMT2AABCB1MAPT | |
| SCHEMBL6934068 | 0.82 | MAPT (0.56) | MEN1KMT2AABCB1MAPTALDH1A1 | |
| SCHEMBL1380552 | 0.80 | MEN1 (0.42) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL5364972 | 0.80 | MEN1 (0.42) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL6938506 | 0.79 | PRMT5 (0.46) | CACNA1GABCB1MAPTALDH1A1PRMT5 | |
| SCHEMBL5360123 | 0.76 | HTR2A (0.48) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL5368832 | 0.76 | HTR2A (0.48) | ADRB3MEN1KMT2ACACNA1GABCB1 | |
| SCHEMBL5360117 | 0.76 | HTR2A (0.48) | ADRB3MEN1KMT2ACACNA1GABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003509432-A | — | — | 2003-03-11 | — | — | JP | claimed |
| EP-1216250-A1 | THIENOISOXAZOLYL AND THIENYLPYRRAZOLYL PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001019833-A1 | THIENOISOXAZOLYL- AND THIENYLPYRRAZOLYL-PHENOXY SUBSTITUTED PROPYL DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |