Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935828 | 1.00 | GAA (0.46) | GAARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6935825 | 1.00 | GAA (0.46) | GAARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30437149 | 1.00 | GAA (0.46) | GAARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6935703 | 0.87 | GAA (0.47) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL6935698 | 0.87 | GAA (0.47) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL7170893 | 0.87 | GAA (0.43) | GAARAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL7170890 | 0.87 | GAA (0.43) | GAARAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL946028 | 0.76 | LMNA (0.55) | GAARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3305713 | 0.75 | GAA (0.44) | GAARAB9AMAPTNPSR1JAK2 | |
| SCHEMBL3305720 | 0.75 | GAA (0.44) | GAARAB9AMAPTNPSR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |