Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935698 | 1.00 | GAA (0.47) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL30437149 | 0.87 | GAA (0.46) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL6935826 | 0.87 | GAA (0.46) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL6935825 | 0.87 | GAA (0.46) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL6935828 | 0.87 | GAA (0.46) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL23301981 | 0.84 | ALDH1A1 (0.43) | GAAMAPTRAB9APOLBHPGD | |
| SCHEMBL23301982 | 0.84 | ALDH1A1 (0.43) | GAAMAPTRAB9APOLBHPGD | |
| SCHEMBL946028 | 0.77 | LMNA (0.55) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL3305713 | 0.77 | GAA (0.44) | GAAMAPTRAB9ANPSR1JAK2 | |
| SCHEMBL3305720 | 0.77 | GAA (0.44) | GAAMAPTRAB9ANPSR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566547-B1 | 3-alkoxy-2-phenylacrylic acid derivatives | ZENECA LIMITED (GB) | 2003-05-20 | — | — | US | disclosed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-5315025-A | Acrylate ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-24 | — | — | US | disclosed |
| US-5286894-A | Phenyl acrylic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| EP-0431328-A2 | Fungicides | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0178826-A2 | Fungicides | ZENECA LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |