Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459900 | 0.87 | CA12 (0.61) | MAOAMCL1ACHECA12CA1 | |
| SCHEMBL30486066 | 0.87 | CA12 (0.61) | MAOAMCL1ACHECA12CA1 | |
| SCHEMBL28544150 | 0.77 | NFKB1 (0.61) | MAOAMCL1CA12CA9ALDH1A1 | |
| SCHEMBL1635601 | 0.77 | AHR (0.68) | MAOANQO1ALDH1A1AHRCYP1A2 | |
| Diethylamine SCHEMBL28338576 | 0.77 | RECQL (0.51) | MAOAMCL1ACHECA12CA1 | |
| SCHEMBL2672376 | 0.76 | MCL1 (0.65) | MAOAMCL1CA12CA1CA9 | |
| SCHEMBL8706801 | 0.75 | MCL1 (1.00) | MCL1CA12CA1CA9ALDH1A1 | |
| SCHEMBL28145932 | 0.74 | MCL1 (0.58) | MAOAMCL1ACHECA12CA1 | |
| SCHEMBL24523033 | 0.73 | ALDH1A1 (0.58) | MCL1CA12CA1CA9RECQL | |
| SCHEMBL12919918 | 0.73 | MCL1 (0.61) | MCL1ACHENQO1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957891-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-03-19 | — | — | EP | claimed |
| US-6037326-A | APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE | GILLETTE COMPANY, THE | 2000-03-14 | — | — | US | claimed |
| EP-0957891-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6037326-A | APPLYING TO THE SKIN AN INHIBITOR OF A DNA TOPOISOMERASE | GILLETTE COMPANY, THE | 2000-03-14 | — | — | US | disclosed |
| EP-0957891-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998029086-A1 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1998-07-09 | — | — | WO | disclosed |