Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593915 | 1.00 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| Urethane SCHEMBL10734204 | 0.92 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28401182 | 0.90 | ALDH1A1 (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL26588350 | 0.89 | NLRP3 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17856292 | 0.88 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7921939 | 0.87 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL840955 | 0.86 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1955909 | 0.86 | NLRP3 (0.80) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13506223 | 0.85 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1601240 | 0.85 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162362-A | CONDESATION OF N-ARYL CARBAMIC ACID ESTER WITH FORMALDEHYDE IN THE PRESENCE OF A SULFONIC ACID | ATLANTIC RICHFIELD COMPANY (US) | 1979-07-24 | — | — | US | claimed |
| EP-3044190-B1 | BURN RATE MODIFIER | THALES AUSTRALIA LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| CN-112020493-B | Method for producing urethane and method for producing isocyanate | 旭化成株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-3720833-A1 | PROPELLANT CHARGE | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO (NL) | 2020-10-14 | — | — | EP | disclosed |
| EP-3621952-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | AlzChem Trostberg GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3044191-B1 | BURN RATE MODIFIER | THALES AUSTRALIA LTD (AU) | 2019-11-20 | — | — | EP | disclosed |
| US-20190210938-A1 | PROPELLANT STABILIZER | THALES AUSTRALIA LIMITED (AU) | 2019-07-11 | — | — | US | disclosed |
| WO-2019112437-A1 | PROPELLANT CHARGE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-06-13 | — | — | WO | disclosed |
| CN-109641835-A | Method for producing carbamate | 国立研究开发法人产业技术综合研究所 | 2019-04-16 | — | — | CN | disclosed |
| US-10196323-B2 | Burn rate modifier | THALES AUSTRALIA LIMITED (AU) | 2019-02-05 | — | — | US | disclosed |
| US-4278805-A | FROM AROMATIC AMINE, CARBAMATE AND ALCOHOL; METAL COMPOUND CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0027954-A1 | Process for preparing urethanes and their use in the preparation of isocyanates | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |
| US-4266070-A | CARBONYLS OF COBALT, MOLYBDENUM, TITANIUM, RHODIUM, IRON, NICKEL AND IRIDIUM AS CATALYSTS FOR THE CARBONYLATION OF PRIMARY OR SECONDARY AMINES AND ALCOHOLS TO FORM CARBAMATES | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-05-05 | — | — | US | disclosed |
| US-4259511-A | Process for separating selenium, selenium compounds, sulfur and/or sulfur compounds from polyurethanes containing these elements and/or compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-31 | — | — | US | disclosed |
| US-4243815-A | Preparation of methylene-bis(4-phenylcarbamic acid esters) | BASF AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4230877-A | ACID CATALYZED CONDENSATION OF AN N-ARYL CARBAMIC ACID ESTER WITH A CARBONYL COMPOUND | ATLANTIC RICHFIELD COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| EP-0014406-A1 | Process for the separation of selenium, selenium compounds, sulfur and/or sulfur compounds from urethanes containing these elements and/or compounds | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |
| US-4151154-A | COUPLERS, SURFACTANTS | UNION CARBIDE CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4136080-A | REINFORCED WITH A SILANE - TREATED ALUMINA HYDRATE | UNION CARBIDE CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |
| US-4105465-A | COATED WITH A SILANE CONTAINING HYDROLYZABLE GROUPS AND A POLYALKYLENE OXIDE GROUP | UNION CARBIDE CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |