Arginine

Arginine

SCHEMBL693611

N=C(N)NCCCC(N)C(=O)O.NC(Cc1c[nH]cn1)C(=O)O.NCCCCC(N)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACES1PR1S1PR4S1PR5

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.42
MMP2 P08253 1/20 0.35
OTC P00480 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
NPY4R P50391 4/20 0.34
NPY1R P25929 3/20 0.34
NPY2R P49146 2/20 0.34
NPY5R Q15761 2/20 0.34
THRB P10828 1/20 0.34
DDAH1 O94760 1/20 0.33
ARG1 P05089 1/20 0.33
CPB1 P15086 1/20 0.33
CPB2 Q96IY4 1/20 0.33
C5AR1 P21730 1/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL28491547 1.00 GSR (0.42) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL14764665 1.00 GSR (0.42) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL29263954 1.00 GSR (0.42) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL1063567 1.00 GSR (0.42) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL15525634 0.99 GSR (0.41) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL20918548 0.96 GSR (0.39) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL2337389 0.96 GSR (0.39) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL25294109 0.95 GSR (0.38) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL8314691 0.95 GSR (0.38) GSRMMP2OTCITGB3ITGA2B
Arginine SCHEMBL1537331 0.95 OTC (0.38) OTCNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5328935-A None JP disclosed
EP-4713004-A1 TREATMENT OF A HEADACHE DISORDER WITH A BOTULINUM NEUROTOXIN A Ipsen Biopharm Limited (GB) 2026-03-25 EP disclosed
EP-4594341-A1 CLOSTRIDIAL NEUROTOXINS COMPRISING AN ACTIVATING EXOGENOUS PROTEASE CLEAVAGE SITE Ipsen Biopharm Limited (GB) 2025-08-06 EP disclosed
EP-4593873-A1 CLOSTRIDIAL NEUROTOXIN FOR USE IN A TREATMENT OF BLADDER PAIN SYNDROME Ipsen Biopharm Limited (GB) 2025-08-06 EP disclosed
EP-4587585-A1 CELL-FREE CLOSTRIDIAL NEUROTOXIN ASSAYS Ipsen Biopharm Limited (GB) 2025-07-23 EP disclosed
WO-2025125793-A1 FORMULATION IPSEN BIOPHARM LIMITED (GB) 2025-06-19 WO disclosed
WO-2025093844-A1 USE OF CHIMERIC BOTULINUM TOXIN A FOR TREATING BLEPHAROSPASM AND HEMIFACIAL SPASM IPSEN BIOPHARM LIMITED (GB) 2025-05-08 WO disclosed
WO-2025093845-A1 USE OF HIGH DOSE CHIMERIC BOTULINUM TOXIN A FOR THE TREATMENT OF UPPER FACIAL LINES IPSEN BIOPHARM LIMITED (GB) 2025-05-08 WO disclosed
EP-4514314-A1 TREATMENT OF UPPER FACIAL LINES Ipsen Biopharm Limited (GB) 2025-03-05 EP disclosed
EP-4514378-A1 TREATMENT OF CERVICAL DYSTONIA Ipsen Biopharm Limited (GB) 2025-03-05 EP disclosed
WO-1996017067-A1 METHOD FOR SECRETING THROMBOPOIETIN POLYPEPTIDES ZYMOGENETICS, INC. (US) 1996-06-06 WO disclosed
WO-1996017062-A1 LOW MOLECULAR WEIGHT THROMBOPOIETIN ZYMOGENETICS, INC. (US) 1996-06-06 WO disclosed
WO-1996011263-A1 ENZYME FOR CLEAVAGE OF THE ANCHOR REGION OF SURFACE PROTEINS FROM GRAM POSITIVE BACTERIA ROCKEFELLER UNIVERSITY (US) 1996-04-18 WO disclosed
WO-1995030758-A1 RECOMBINANT HK2 POLYPEPTIDE MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1995-11-16 WO disclosed
WO-1995021920-A1 HEMATOPOIETIC PROTEIN AND MATERIALS AND METHODS FOR MAKING IT ZYMOGENETICS, INC. (US) 1995-08-17 WO disclosed
WO-1995021626-A1 METHODS FOR STIMULATING ERYTHROPOIESIS USING THROMBOPOIETIN UNIVERSITY OF WASHINGTON (US) 1995-08-17 WO disclosed
CN-1095481-A Measure juvenile cell reagent TOA MEDICAL ELECTRONICS (JP) 1994-11-23 CN disclosed
CN-1089796-A The infant strengthens series food and production method thereof DIDUOLI FOOD CO LTD BEILIU COU (CN) 1994-07-27 CN disclosed
JP-H05328935-A FLAVOR IMPROVER SB SHOKUHIN KK 1993-12-14 JP disclosed
WO-1984003044-A1 ENZYME INHIBITORS FERRING AB (SE) 1984-08-16 WO disclosed