SCHEMBL6936145

SCHEMBL6936145

CC(=O)OC(C)N1CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA3 P07451 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
PIK3CD O00329 1/20 0.38
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935129 0.95 LMNA (0.42) LMNACA12CA1CA2CA3
SCHEMBL6936360 0.93 LMNA (0.41) LMNACA12CA1CA2CA3
SCHEMBL4154528 0.85 LMNA (0.44) LMNACA12CA1CA2CA3
SCHEMBL28531475 0.84 LMNA (0.46) LMNACA12CA1CA2CA3
SCHEMBL19146022 0.83 LMNA (0.45) LMNACA12CA1CA2CA3
SCHEMBL26972384 0.83 LMNA (0.45) LMNACA12CA1CA2CA3
SCHEMBL9476063 0.82 LMNA (0.47) LMNACA12CA1CA2CA3
SCHEMBL6931168 0.81 LMNA (0.44) LMNACA12CA1CA2CA3
SCHEMBL9477427 0.81 LMNA (0.46) LMNACA12CA1CA2CA3
SCHEMBL4151214 0.80 LMNA (0.43) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8239354-A None JP disclosed
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof ISP INVESTMENTS LLC (US) 2020-04-28 US disclosed
CN-101239938-B Method for preparing (S)-4-hydroxypyrrolidone and derivatives thereof SUZHOU CHIREACH BIOMEDICAL TECHNOLOGY CO LTD 2010-08-25 CN disclosed
CN-101239938-A Method for preparing (S)-4-hydroxypyrrolidone and derivatives thereof SUZHOU CHIREACH BIOMEDICAL TEC (CN) 2008-08-13 CN disclosed
EP-0703219-B2 Method for the preparation of an N-vinyl compound JAPAN VAM & POVAL CO LTD (JP) 2003-04-02 EP disclosed
EP-0703219-B1 Method for the preparation of an N-vinyl compound SHIN ETSU VINYL (JP) 2000-09-20 EP disclosed
EP-0699664-B1 N-(aLpha-acyloxyethyl) compound and method for the preparation thereof SHIN ETSU VINYL ACETATE CO LTD (JP) 1998-09-23 EP disclosed
US-5708167-A FORMING A VINYL GROUP BY REMOVAL OF ACYLOXY GROUP FROM ETHYL ON HETERO RING SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1998-01-13 US disclosed
US-5708167-A FORMING A VINYL GROUP BY REMOVAL OF ACYLOXY GROUP FROM ETHYL ON HETERO RING SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1998-01-13 US disclosed
US-5608057-A N-(alpha-acyloxyethyl) compound and method for the preparation thereof SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1997-03-04 US disclosed
US-5608057-A N-(alpha-acyloxyethyl) compound and method for the preparation thereof SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1997-03-04 US disclosed
JP-H08239354-A N-(ALPHA-ACYLOXYETHYL) COMPOUND AND ITS PRODUCTION SHINETSU SAKUSAN VINYL KK 1996-09-17 JP disclosed
EP-0703219-A1 Method for the preparation of an N-vinyl compound SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1996-03-27 EP disclosed
EP-0703219-A1 Method for the preparation of an N-vinyl compound SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1996-03-27 EP disclosed
EP-0699664-A1 N-(aLpha-acyloxyethyl) compound and method for the preparation thereof SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1996-03-06 EP disclosed
EP-0699664-A1 N-(aLpha-acyloxyethyl) compound and method for the preparation thereof SHIN-ETSU VINYL ACETATE CO., LTD. (JP) 1996-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof C9, PARG, C5 LMNA 154/4885CA12 3093/4885CA1 2470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.