SCHEMBL4154528

SCHEMBL4154528

C=C(C)C(=O)OC(C)N1CCCC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
KMT2A Q03164 2/20 0.37
ATM Q13315 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19145906 0.94 LMNA (0.39) LMNACA12CA1CA2CA3
SCHEMBL11734817 0.88 LMNA (0.40) LMNACA12CA1CA2CA3
SCHEMBL6936145 0.85 LMNA (0.47) LMNACA12CA1CA2CA3
SCHEMBL15909726 0.83 LMNA (0.41) LMNACA12CA1CA2CA3
SCHEMBL11734829 0.82 LMNA (0.40) LMNACA12CA1CA2CA3
SCHEMBL2036449 0.81 KMT2A (0.43) LMNACA12CA1CA2CA3
SCHEMBL15909729 0.81 TSHR (0.46) LMNACA12CA1CA2CA3
SCHEMBL1817230 0.80 ALDH1A1 (0.44) LMNACA12CA1CA2CA3
SCHEMBL8854339 0.80 LMNA (0.41) LMNACA12CA1CA2CA3
SCHEMBL6935129 0.80 LMNA (0.42) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478942-A Polycarboxylate superplasticizer capable of effectively resisting influence of flocculating agent and preparation method thereof 四川同舟化工科技有限公司 2022-05-13 CN claimed
US-20180327628-A1 COATING COMPOSITIONS FOR FORMING TONER COATINGS ISP INVESTMENTS LLC (US) 2018-11-15 US claimed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
CN-114478942-A Polycarboxylate superplasticizer capable of effectively resisting influence of flocculating agent and preparation method thereof 四川同舟化工科技有限公司 2022-05-13 CN disclosed
CN-114478942-A Polycarboxylate superplasticizer capable of effectively resisting influence of flocculating agent and preparation method thereof 四川同舟化工科技有限公司 2022-05-13 CN disclosed
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof HERCULES LLC (US) 2021-05-11 US disclosed
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2021-02-02 US disclosed
US-20200407470-A1 METHODS OF SYNTHESIS OF HOMOPOLYMERS AND NON-HOMOPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES IN AN AQUEOUS MEDIUM ISP INVESTMENTS LLC (US) 2020-12-31 US disclosed
US-10876015-B2 Coating compositions for forming toner coatings ISP INVESTMENTS LLC (US) 2020-12-29 US disclosed
US-6132462-A HYDROXYALKYL (ALKYL)ACRYLATE; PYRROLIDONE-CONTAINING ACRYLIC ESTER, AMIDE, OR IMIDE; AND A LOWER ALKYL (ALKYL)ACRYLATE TERPOLYMER; FOLDABLE LENSE HAVING GIVEN REFRACTIVE INDEX, RECOVERY SPEED FROM FOLD STATE AND TENSILE STRENGTH SANTEN PHARMACEUTICAL CO., LTD. (JP) 2000-10-17 US disclosed
EP-1026182-A1 FOUR COMPONENT COPOLYMER AND THE OCULAR LENS MADE THEREOF SANTEN PHARMACEUTICAL CO., LTD (JP) 2000-08-09 EP disclosed
EP-0987247-A1 ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER SANTEN PHARMACEUTICAL CO., LTD. (JP) 2000-03-22 EP disclosed
CN-1213671-A Four-component copolymer and eye lens formed by same SANTEN PHARMACEUTICAL CO LTD (JP) 1999-04-14 CN disclosed
EP-0869138-A1 NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF SANTEN PHARMACEUTICAL CO., LTD. (JP) 1998-10-07 EP disclosed
CN-1152584-A Three constituents copolymer and eye lens made from it SANTEN PHARMACEUTICAL CO LTD (JP) 1997-06-25 CN disclosed
US-5629359-A OXO-PYRROLIDINYL (METH)ACRYLIC ESTER U C B S.A. (BE) 1997-05-13 US disclosed
US-5188770-A Polyalkyl (meth)acrylates as oil additives Rphm GmbH (DE) 1993-02-23 US disclosed
US-3968148-A Copolymers of 1-alkenes and acrylic acid derivatives ROHM AND HAAS COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS LMNA 2499/4885CA12 1204/4885CA1 867/4885
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof F9, ADCY9, MMS19 LMNA 2191/4885CA12 2531/4885CA1 3645/4885
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof CAD, STS, COASY LMNA 1683/4885CA12 1078/4885CA1 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.