Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165118 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL10654350 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL9736591 | 0.90 | KMT2A (0.46) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL9736585 | 0.90 | KMT2A (0.46) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL7170181 | 0.89 | KMT2A (0.49) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL10654355 | 0.89 | ALDH1A1 (0.52) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL9944266 | 0.84 | HPGD (0.41) | ALDH1A1HTTLMNAKDM4ETSHR | |
| SCHEMBL7658965 | 0.82 | HPGD (0.46) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL7658957 | 0.82 | HPGD (0.46) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL7658954 | 0.82 | HPGD (0.46) | ALDH1A1LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |