Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 4/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936259 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL10654350 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL7165118 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL8814593 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL27519602 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL8179369 | 0.81 | HPGD (0.49) | ALDH1A1LMNAKDM4EL3MBTL1TSHR | |
| SCHEMBL9021316 | 0.80 | HDAC3 (0.42) | ALDH1A1LMNAKMT2A | |
| SCHEMBL6156562 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HTTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8035923 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HTTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9267454 | 0.80 | HDAC3 (0.42) | ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782177-A | AGRICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | claimed |
| US-4782177-A | AGRICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |