Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657665 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL5071228 | 0.76 | RXFP1 (0.62) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL14292869 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL27856323 | 0.71 | ALDH1A1 (0.69) | ALDH1A1MAPTRAB9ANPC1TP53 | |
| SCHEMBL21568085 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL29764757 | 0.70 | MAPT (0.53) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL23147334 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL209203 | 0.69 | MAPT (0.69) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL31598537 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MAPTRAB9ANPC1CYP2C19 | |
| SCHEMBL30890711 | 0.68 | MAPT (0.58) | ALDH1A1MAPTRAB9ANPC1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009943-A1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |