Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.60 |
| ▸ | PPARD | Q03181 | 11/20 | 0.60 |
| ▸ | PPARA | Q07869 | 10/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936744 | 1.00 | PPARG (0.60) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6936087 | 0.92 | PPARD (0.71) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6936091 | 0.92 | PPARD (0.71) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6934065 | 0.90 | PPARD (0.58) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6936719 | 0.84 | PPARG (0.85) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6935493 | 0.84 | PPARG (0.85) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6936329 | 0.82 | PPARG (0.53) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6937010 | 0.81 | PPARG (0.68) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL6931405 | 0.81 | PPARD (0.69) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL5203913 | 0.81 | PPARG (0.52) | PPARGPPARDPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |