Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936800 | 0.85 | ALDH1A1 (0.49) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| Acetic Acid SCHEMBL28784357 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| Acetic Acid SCHEMBL8540615 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| Acetic Acid SCHEMBL6056055 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL6514301 | 0.75 | ALDH1A1 (0.65) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL5403337 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| Acetic Acid SCHEMBL306033 | 0.74 | SLC6A2 (0.53) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| Acetic Acid SCHEMBL15865238 | 0.74 | SLC6A2 (0.53) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL28168069 | 0.74 | ALDH1A1 (0.67) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL25846939 | 0.74 | ALDH1A1 (0.54) | ALDH1A1RECQLSMN1; SMN2HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649604-B2 | Analgesics; antidiabetic agents; antiinflamamtory agents | AMGEN INC. | 2003-11-18 | — | — | US | disclosed |