Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275738 | 0.86 | CA2 (0.50) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL19480330 | 0.84 | GBA1 (0.45) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL14778660 | 0.83 | CA2 (0.42) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL6934729 | 0.81 | CA2 (0.39) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL18900446 | 0.81 | CA2 (0.43) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL5551724 | 0.81 | PPARG (0.41) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL11188915 | 0.79 | DHODH (0.39) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL11185625 | 0.79 | DHODH (0.39) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL7147511 | 0.79 | CA2 (0.40) | GBA1ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL18900536 | 0.78 | ALDH1A1 (0.42) | GBA1ALDH1A1MEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |