SCHEMBL6936827

SCHEMBL6936827

CCOc1ccc(C=Nc2ccc(C(C)=CC(=O)O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46
CASP3 P42574 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PLEC Q15149 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
CA2 P00918 5/20 0.46
CA1 P00915 4/20 0.46
NPC1 O15118 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12416947 0.87 CA2 (0.61) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12417133 0.87 CA2 (0.61) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12416660 0.87 L3MBTL1 (0.50) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL19460597 0.87 L3MBTL1 (0.50) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL19460778 0.82 KMT2A (0.57) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12416627 0.82 KMT2A (0.57) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL9556747 0.82 NPC1 (0.56) SMN1; SMN2KDM4EALDH1A1KMT2AMAPT
SCHEMBL11682122 0.81 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL11682120 0.81 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL17732338 0.81 CA2 (0.68) SMN1; SMN2KDM4EALDH1A1L3MBTL1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170115491-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2017-04-27 US disclosed
EP-1372023-A2 Electro-optically concealable vehicle instrument panel and method of constructing the same Ergom Automotive S.p.a. (IT) 2003-12-17 EP disclosed