Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 13/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698985 | 0.83 | ALDH1A1 (0.51) | PPARA | |
| SCHEMBL6698978 | 0.78 | PTPN1 (0.45) | ACACB | |
| SCHEMBL6700671 | 0.77 | TAAR1 (0.47) | — | |
| SCHEMBL6936866 | 0.73 | ACACB (0.41) | PPARAACACBPPARG | |
| SCHEMBL6713266 | 0.72 | MEN1 (0.49) | PPARAACACBLDHAPPARG | |
| SCHEMBL6931950 | 0.71 | PPARA (0.43) | PPARAACACBLDHAPPARG | |
| SCHEMBL29641573 | 0.71 | ITGB3 (0.61) | PPARALDHA | |
| SCHEMBL30605287 | 0.71 | ITGB3 (0.61) | PPARALDHA | |
| SCHEMBL30605290 | 0.70 | ITGB3 (0.47) | PPARALDHAPPARG | |
| SCHEMBL29641765 | 0.70 | ITGB3 (0.46) | PPARAACACBLDHAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |