Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704698 | 0.73 | — | — | |
| SCHEMBL6936615 | 0.70 | PPARG (0.36) | PPARGPPARAPTPN1PTPN11 | |
| SCHEMBL5704708 | 0.67 | PPARG (0.34) | PPARGPPARAPTPN1PTPN11 | |
| SCHEMBL147801 | 0.65 | CNR1 (0.37) | ALDH1A1CYP3A4PTPN1PTPN11 | |
| SCHEMBL18242227 | 0.65 | PTPN1 (0.31) | PTPN1PTPN11 | |
| SCHEMBL18242211 | 0.63 | PTPN1 (0.32) | ALDH1A1CYP3A4PTPN1PTPN11 | |
| SCHEMBL18242176 | 0.61 | PTPN1 (0.33) | ALDH1A1CYP3A4PTPN1PTPN11 | |
| SCHEMBL5048782 | 0.61 | PTGS2 (0.33) | CYP3A4 | |
| SCHEMBL16961649 | 0.61 | PTPN1 (0.46) | ALDH1A1CYP3A4PTPN1PTPN11MTNR1A | |
| SCHEMBL7299326 | 0.60 | PTPN1 (0.36) | ALDH1A1CYP3A4PTPN1PTPN11MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |