SCHEMBL6937124

SCHEMBL6937124

Cc1cc(NC(=O)Cc2cc(C(=N)N)ccc2O)ccc1-c1c2c(nn1C)CCC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 8/20 0.37
PRSS1 P07477 6/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TMPRSS2 O15393 1/20 0.35
HTR1D P28221 1/20 0.35
SLC6A4 P31645 1/20 0.35
ANO1 Q5XXA6 3/20 0.34
PLAU P00749 2/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
F2 P00734 6/20 0.33
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
PLAT P00750 1/20 0.33
F9 P00740 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7072487 0.99 F10 (0.36) F10PRSS1MEN1KMT2AALDH1A1
SCHEMBL6937674 0.87 MAPT (0.37) F10PRSS1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL7069690 0.86 MAPT (0.37) F10PRSS1MEN1KMT2AALDH1A1
SCHEMBL6941083 0.84 F10 (0.37) F10PRSS1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL6938777 0.83 F10 (0.37) F10PRSS1MEN1KMT2AALDH1A1
SCHEMBL6940983 0.81 TTK (0.37) F10PRSS1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL7562492 0.80 TTK (0.37) F10PRSS1MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL7074489 0.77 MAPT (0.37) F10PRSS1MEN1KMT2AALDH1A1
SCHEMBL6942538 0.75 KDR (0.42) F10PRSS1PLAUMAPTF2
SCHEMBL6941666 0.75 F10 (0.39) F10PRSS1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1370540-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-17 EP claimed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US claimed
WO-2002072558-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-19 WO claimed
EP-1370540-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-17 EP disclosed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed
WO-2002072558-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 F10 33/4885PRSS1 1106/4885MEN1 2312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.