SCHEMBL6942538

SCHEMBL6942538

Cc1nn(-c2ccc(NC(=O)Cc3cc(C(=N)N)ccc3O)cc2)c2c1CCC2

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDR P35968 2/20 0.42
F10 P00742 2/20 0.40
PRSS1 P07477 2/20 0.40
CSF1R P07333 13/20 0.39
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
F2 P00734 1/20 0.37
PLAU P00749 1/20 0.37
PLAT P00750 1/20 0.37
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
KLK6 Q92876 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7074489 0.89 MAPT (0.37) KDRF10PRSS1CSF1RTP53
SCHEMBL7562213 0.79 MAPT (0.35) KDRF10PRSS1CSF1RTP53
SCHEMBL7568090 0.79 MAPT (0.39) F10PRSS1TP53MAPTF2
SCHEMBL6937674 0.79 MAPT (0.37) KDRF10PRSS1TP53MAPT
Hydrochloric Acid SCHEMBL7562852 0.78 MAPT (0.34) KDRF10PRSS1CSF1RTP53
Hydrochloric Acid SCHEMBL7071483 0.78 MAPT (0.38) F10PRSS1TP53MAPTF2
Hydrochloric Acid SCHEMBL7069690 0.78 MAPT (0.37) KDRF10PRSS1TP53MAPT
Hydrochloric Acid SCHEMBL7563584 0.77 F10 (0.38) F10PRSS1MAPT
SCHEMBL6937124 0.75 F10 (0.37) F10PRSS1MAPTF2PLAU
Hydrochloric Acid SCHEMBL7072487 0.75 F10 (0.36) F10PRSS1MAPTF2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US claimed
EP-1370540-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-17 EP disclosed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed
WO-2002072558-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 KDR 943/4885F10 33/4885PRSS1 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.