Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932144 | 0.91 | MMP2 (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6932836 | 0.88 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6934343 | 0.79 | GPBAR1 (0.59) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6932236 | 0.76 | CYSLTR1 (0.65) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6090813 | 0.74 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9152799 | 0.72 | CYP2C9 (0.57) | — | |
| SCHEMBL6932132 | 0.72 | GPBAR1 (0.60) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6932107 | 0.71 | MMP2 (0.70) | — | |
| SCHEMBL5658878 | 0.70 | CYP2C9 (0.66) | — | |
| SCHEMBL4720632 | 0.70 | HDAC1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |