Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363035 | 0.88 | MMP2 (0.71) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL6932107 | 0.87 | MMP2 (0.70) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL9148637 | 0.87 | MMP2 (0.49) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL3765157 | 0.83 | HPGD (0.78) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL5658878 | 0.81 | CYP2C9 (0.66) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL316248 | 0.81 | MMP2 (0.85) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL11006463 | 0.79 | CYP2C9 (0.60) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL4438683 | 0.78 | CYP2C9 (0.69) | CYP2C9HPGDCYP2C19MMP2MMP9 | |
| SCHEMBL9288801 | 0.76 | CAMK2A (0.63) | CAMK2AGAAFFAR1AKR1C3SRD5A2 | |
| SCHEMBL3889251 | 0.76 | LTA4H (0.55) | GAASMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468857-A | Phenylmethoxypropenoic esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-21 | — | — | US | disclosed |
| EP-0307103-B1 | Fungicides | ZENECA LTD (GB) | 1994-09-21 | — | — | EP | disclosed |
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| EP-0307103-A2 | Fungicides | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |