Pyridine

Pyridine

SCHEMBL693725

OB(O)F.OB(O)F.OB(O)F.OB(O)F.c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
NAPRT Q6XQN6 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL6310895 1.00 TSHR (0.60) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL10815564 1.00 TSHR (0.60) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL9066090 1.00 TSHR (0.60) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL28110589 0.93 TSHR (0.60) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL7994810 0.93 TSHR (0.60) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL31024706 0.86 TSHR (0.69) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL432431 0.86 TSHR (0.69) TSHRNAPRTTDP1NOTUM
Benzene SCHEMBL28078567 0.86 TSHR (0.69) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL1172941 0.86 TSHR (0.69) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL3103106 0.86 TSHR (0.69) TSHRNAPRTTDP1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2583096-A1 METHOD FOR DETECTING PEROXIDE EXPLOSIVES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2013-04-24 EP claimed
WO-2011157801-A1 METHOD FOR DETECTING PEROXIDE EXPLOSIVES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2011-12-22 WO claimed
EP-2443078-A2 ODOR SAMPLES OF PEROXIDIC EXPLOSIVES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2012-04-25 EP disclosed
EP-2421623-A1 METHOD FOR SEPARATING AROMATIC COMPOUNDS LANXESS Deutschland GmbH (DE) 2012-02-29 EP disclosed
WO-2010146170-A2 ODOR SAMPLES OF PEROXIDIC EXPLOSIVES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2010-12-23 WO disclosed
WO-2010122073-A1 METHOD FOR SEPARATING AROMATIC COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2010-10-28 WO disclosed
US-7144993-B2 Process for the preparation of 4-methyl-7-aminoquinolones CIBA SPECIALTY CHEMICALS CORP. (US) 2006-12-05 US disclosed
US-20050222397-A1 Process for the preparation of 4-methyl-7-aminoquinolones CIBA SPECIALTY CHEMICALS CORP. 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222397-A1 Process for the preparation of 4-methyl-7-aminoquinolones CBR1, CBR3, MRPL21 TSHR 2965/4885NAPRT 2103/4885TDP1 2507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.