Pyridine

Pyridine

SCHEMBL1172941

OB(O)O.c1ccncc1.c1ccncc1.c1ccncc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
NAPRT Q6XQN6 2/20 0.69
NOTUM Q6P988 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
APP P05067 1/20 0.31
GAA P10253 1/20 0.31
HCAR3 P49019 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28078567 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL432431 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL31024706 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL3281597 0.96 TSHR (0.64) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL31655458 0.96 TSHR (0.64) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL6532110 0.88
Pyridine SCHEMBL28067297 0.88 NAPRT (0.90) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL8023624 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM
Pyridine SCHEMBL7994810 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM
Pyridine SCHEMBL10815564 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535311-A Novel synthesis method of Carbonic acid 风火轮(上海)生物科技有限公司 2023-08-04 CN claimed
JP-9194816-A None JP disclosed
JP-10251317-A None JP disclosed
CN-116535311-A Novel synthesis method of Carbonic acid 风火轮(上海)生物科技有限公司 2023-08-04 CN disclosed
CN-115028849-B Preparation method and application of metal triangle supermolecule with room temperature fluorescence 广州大学 2023-06-16 CN disclosed
CN-116072970-A Lithium ion battery electrolyte, lithium ion battery and electric equipment 广汽埃安新能源汽车股份有限公司 2023-05-05 CN disclosed
CN-112912047-A Microneedle array patch with glucose responsive matrix for closed-loop insulin delivery 北卡罗莱纳州立大学 2021-06-04 CN disclosed
US-8343382-B2 Band gap control in conjugated oligomers and polymers via Lewis acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-01 US disclosed
US-20110028656-A1 Band gap control in conjugated oligomers and polymers via Lewis acids NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2011-02-03 US disclosed
JP-2003238572-A METHOD FOR PRODUCING PYRIDINE-TRI(SUBSTITUTED OR NON- SUBSTITUTED PHENYL)BORANE COMPLEX HOKKO CHEM IND CO LTD 2003-08-27 JP disclosed
WO-2002081551-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS DOW CORNING CORPORATION (US) 2002-10-17 WO disclosed
JP-H10251317-A POLYMERIZATION INITIATOR, POLYMERIZABLE COMPOSITION AND CURED PRODUCT OF THE COMPOSITION TOYO INK MFG CO LTD 1998-09-22 JP disclosed
JP-H09194816-A ENERGY RADIATION-SENSITIVE ACID-GENERATING AGENT, ENERGY RADIATION-SENSITIVE ACID-GENERATING AGENT COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT THEREOF TOYO INK MFG CO LTD 1997-07-29 JP disclosed
US-5565363-A DETECTING MIXTURE COMPRISING ONE OR MORE BUFFERS, PH INDICATORS AND SURFACTANTS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-10-15 US disclosed
US-4091847-A Process for filling dynamic scattering liquid crystal cells RCA CORPORATION (US) 1978-05-30 US disclosed
US-4033905-A SUCH AS SILICONE RUBBERS, THERMOPLASTIC RESINS AND LIQUID CRYSTALS, USING PYRIDINIUM BORATES RCA CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028656-A1 Band gap control in conjugated oligomers and polymers via Lewis acids PCNA, CLTB, GJB2 TSHR 4029/4885TDP1 3934/4885NAPRT 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.