Pyridine

Pyridine

SCHEMBL432431

OB(O)O.c1ccncc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
NAPRT Q6XQN6 2/20 0.69
NOTUM Q6P988 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
APP P05067 1/20 0.31
GAA P10253 1/20 0.31
HCAR3 P49019 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28078567 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL31024706 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL1172941 1.00 TSHR (0.69) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL3281597 0.96 TSHR (0.64) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL31655458 0.96 TSHR (0.64) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL6532110 0.88
Pyridine SCHEMBL28067297 0.88 NAPRT (0.90) TSHRTDP1NAPRTNOTUMMEN1
Pyridine SCHEMBL8023624 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM
Pyridine SCHEMBL7994810 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM
Pyridine SCHEMBL10815564 0.86 TSHR (0.60) TSHRTDP1NAPRTNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12508298-B2 Protein complex by use of a specific site of an immunoglobulin fragment for linkage HANMI PHARM. CO., LTD. (KR) 2025-12-30 US claimed
US-20250197466-A1 METHODS OF TREATMENT USING G-CSF PROTEIN COMPLEX ASSERTIO SPECIALTY PHARMACEUTICALS, LLC 2025-06-19 US claimed
US-20250115953-A1 Methylcytosine-Selective Deaminases and Uses Thereof NEW ENGLAND BIOLABS, INC. (US) 2025-04-10 US claimed
EP-4534107-A2 PROTEIN COMPLEX BY USE OF A SPECIFIC SITE OF AN IMMUNOGLOBULIN FRAGMENT FOR LINKAGE Hanmi Pharm. Co., Ltd. (KR) 2025-04-09 EP claimed
CN-119684330-A Preparation method of bisazo pyridine borate@quantum dot fluorescent probe 北京印刷学院 2025-03-25 CN claimed
CN-117219773-A Positive electrode slurry and preparation method thereof 宁波容百新能源科技股份有限公司 2023-12-12 CN claimed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-116535311-A Novel synthesis method of Carbonic acid 风火轮(上海)生物科技有限公司 2023-08-04 CN claimed
CN-115340543-B Positive ion type cyclopean and application thereof in preparing pharmaceutical preparation for removing photodynamic therapy residues 复旦大学 2023-07-07 CN claimed
CN-108136276-B Protein complexes linked by using specific sites of immunoglobulin fragments 韩美药品株式会社 2023-02-28 CN claimed
WO-2005047336-A1 PROTEIN COMPLEX USING IMMUNOGLOBULIN FRAGMENT ANDMETHOD FOR THE PREPARATION THEREOF HANMI PHARMACEUTICAL. CO. LTD. (KR) 2005-05-26 WO claimed
WO-2004083242-A1 HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR CONJUGATE HAVING ENHANCED STABILITY IN BLOOD AND PROCESS FOR THE PREPARATION THEREOF HANMI PHARM. CO. LTD. (KR) 2004-09-30 WO claimed
WO-2004081053-A1 PHYSIOLOGICALLY ACTIVE POLYPEPTIDE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE HANMI PHARM. CO. LTD. (KR) 2004-09-23 WO claimed
US-20040181035-A1 Modified colony stimulating factor for treatment of hematopoietic disorder AMGEN, INC. 2004-09-16 US claimed
US-20040180054-A1 Physiologically active polypeptide conjugate having prolonged in vivo half-life HANMI PHARM. CO., LTD. 2004-09-16 US claimed
US-20030096400-A1 N-terminally chemically modified protein compositions and methods AMGEN, INC. 2003-05-22 US claimed
US-20030053982-A1 N-terminally chemically modified protein compositions and methods KINSTLER OLAF B (US) 2003-03-20 US claimed
JP-3177251-B2 2001-06-18 JP claimed
EP-0733067-A1 N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS AMGEN INC. (US) 1996-09-25 EP claimed
WO-1996011953-A1 N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS AMGEN INC. (US) 1996-04-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040181035-A1 Modified colony stimulating factor for treatment of hematopoietic disorder CSF3R, GMFG, HCLS1 TSHR 3051/4885TDP1 4057/4885NAPRT 3307/4885
US-20030096400-A1 N-terminally chemically modified protein compositions and methods PTMS, NGLY1, ACP1 TSHR 3426/4885TDP1 2631/4885NAPRT 1323/4885
US-20030053982-A1 N-terminally chemically modified protein compositions and methods PTMS, NGLY1, ACP1 TSHR 3426/4885TDP1 2631/4885NAPRT 1323/4885
US-12508298-B2 Protein complex by use of a specific site of an immunoglobulin fragment for linkage FCGR3B, FCGR2A, FCER2 TSHR 634/4885TDP1 4709/4885NAPRT 4104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.