Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621244 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL21065429 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL28377777 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL17335504 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL8333539 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL2141070 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL821271 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| Ammonia Solution, Strong SCHEMBL28426608 | 0.97 | LMNA (0.43) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL421809 | 0.97 | LMNA (0.41) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL7866893 | 0.92 | TSHR (0.46) | LMNAALDH1A1TSHRDGKAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3694646-A1 | A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM | Metabolon, Inc. (US) | 2020-08-19 | — | — | EP | disclosed |
| WO-2019074757-A1 | A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM | METABOLON, INC. (US) | 2019-04-18 | — | — | WO | disclosed |
| CN-104126012-A | Bioconversion process for producing nylon-7, nylon-7,7 and polyesters | INVISTA TECH SARL | 2014-10-29 | — | — | CN | disclosed |
| CN-104011216-A | Bioconversion process for producing nylon-7, nylon-7,7 and polyesters | INVISTA TECHONOLOGIES S A R L | 2014-08-27 | — | — | CN | disclosed |
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1315962-A | Novel method for synthesizing Exochelins | KEYSTONE BIOMEDICAL INC (US) | 2001-10-03 | — | — | CN | disclosed |
| EP-1105416-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | Keystone Biomedical, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| US-6063919-A | ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) | KEYSTONE BIOMEDICAL, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-2000009547-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | KEYSTONE BIOMEDICAL, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |