Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621244 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL21065429 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL28377777 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL17335504 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL8333539 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL6937280 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL2141070 | 1.00 | LMNA (0.45) | LMNAALDH1A1TSHRDGKAKMT2A | |
| Ammonia Solution, Strong SCHEMBL28426608 | 0.97 | LMNA (0.43) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL421809 | 0.97 | LMNA (0.41) | LMNAALDH1A1TSHRDGKAKMT2A | |
| SCHEMBL7866893 | 0.92 | TSHR (0.46) | LMNAALDH1A1TSHRDGKAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389349-A2 | METHODS FOR PRODUCING DODECANEDIOIC ACID AND DERIVATIVES THEREOF | Draths Corporation (US) | 2011-11-30 | — | — | EP | disclosed |
| US-8041434-B2 | Implantable medical electrical lead bodies providing improved electrode contact | MEDTRONIC, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010085712-A2 | METHODS FOR PRODUCING DODECANEDIOIC ACID AND DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2010-07-29 | — | — | WO | disclosed |