SCHEMBL6937282

SCHEMBL6937282

CC(C)(C)c1ccc(C=O)c(C(Cl)(Cl)Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 4/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
MAPK1 P28482 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395410 0.90 ALDH1A1 (0.39) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL1798644 0.79 MAPT (0.42) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL356134 0.78 MAPT (0.44) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4057549 0.77 TDP1 (0.55) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL9281221 0.76 ALDH1A1 (0.46) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL676421 0.74 ALDH1A1 (0.41) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL20379836 0.73 TDP1 (0.41) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL1527058 0.73 ALDH1A1 (0.57) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL31273152 0.73 ALDH1A1 (0.52) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL31426976 0.73 TDP1 (0.41) ALDH1A1TDP1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542393-B2 Radiation curable polyurethane resin for ink jet ink AGFA NV (BE) 2023-01-03 US disclosed
US-20200369880-A1 RADIATION CURABLE POLYURETHANE RESIN FOR INK JET INK AGFA NV (BE) 2020-11-26 US disclosed
CN-111406081-A Radiation curable polyurethane resins for inkjet inks 爱克发有限公司 2020-07-10 CN disclosed
WO-2020064633-A1 LASER MARKABLE COMPOSITIONS AGFA NV (BE) 2020-04-02 WO disclosed
EP-3626471-A1 LASER MARKABLE COMPOSITIONS AGFA NV (BE) 2020-03-25 EP disclosed
EP-0828195-B1 Method for improving photoimage quality CIBA SC HOLDING AG (CH) 2003-02-19 EP disclosed
US-6045972-A APPLYING A PHOTOCHEMICALLY OR THERMALLY CURABLE EPOXY ACRYLATE RESIN TO FORM A NON-TACKY AND GOOD EDGE COVERINGS; WATERPROOFING CIBA SPECIALTY CHEMICALS CORP. (US) 2000-04-04 US disclosed
US-5942371-A Aqueous acrylic photopolymerisable compositions CIBA SPECIALTY CHEMICALS CORP. (US) 1999-08-24 US disclosed
EP-0828195-A2 Method for improving photoimage quality Ciba SC Holding AG (CH) 1998-03-11 EP disclosed