Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937514 | 0.86 | MEN1 (0.65) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL7623004 | 0.83 | MEN1 (0.58) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL11895913 | 0.80 | MEN1 (0.71) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10713102 | 0.80 | MEN1 (0.79) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10530781 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL10710090 | 0.78 | MEN1 (0.79) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL6815404 | 0.75 | ALDH1A1 (0.63) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL10455797 | 0.75 | MEN1 (0.69) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8018123 | 0.75 | KMT2A (1.00) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL6940827 | 0.74 | KMT2A (0.58) | MEN1KMT2AMAPTLMNACDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-B1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA AS (SK) | 2003-03-05 | — | — | EP | disclosed |
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |